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Fig. 1. The Pitx family of homeobox genes. Alignment of amino acid sequences of the homeo domains of vertebrate Pitx2 (identical in human, mouse, chick, zebrafish, and Xenopus) with Drosophila Pitx (Dpitx), mouse Pitx1 (mPtx1) and mouse goosecoid (mgsc). Only positions that differ from Pitx2 are shown. The lysine residue characteristic of the bicoid group of paired type homeoboxes is shown in bold face. Note that the homeo domain of Drosophila Pitx displays higher homology to vertebrate Pitx2 than to Pitx1.

Image published in: Campione M et al. (1999)

Copyright © 1999. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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