XB-IMG-131093
Xenbase Image ID: 131093
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Fig. 2. Left-sided Pitx2 expression is conserved
between mouse, Xenopus and zebrafish.
(A-D) Pitx2 expression in the mouse from E7.0 to
E9.0. (A) Earliest localized expression of Pitx2 is
seen in two patches in the prospective head
mesenchyme. Anterior view of an E7.0 embryo.
(B) Pitx2 is asymmetrically expressed in the left
LPM and in the left myocardium of the linear
heart tube. Ventral view of a E8.0 embryo (6
somites). hf, headfolds; h, heart; l, left; r, right.
(C,D) Left-sided expression of Pitx2 in the tubular
gut at E9.0. Plane of section in D is indicated by
the line in C. bw, body wall; g, gut; lsp, left
splanchnopleura; rsp, right splanchnopleura; va,
vitelline artery. (E-H) Pitx2 expression in Xenopus
from stage 12 to stage 26. (E-G) From stage 12 to
18 sickle-shaped expression is seen in the cement
gland anlage (E-G) and in two patches of head
mesenchyme (G). (H) At stage 26 strong
expression persists in the cement gland.
Asymmetric expression is seen in the left (top) but
not in the right (bottom) lateral plate mesoderm. l,
left; r, right. (I-L) Pitx2 expression in the zebrafish
embryo from 90% epiboly to 23 hour in the
polster (I-K) and left LPM (L). (I) Animal pole
view of an embryo at 90% epiboly (9 hours).
(J) Animal pole view of a 3 somite embryo (10
hours). (K) Animal pole view of a 11 somite
embryo (14.5 hours). (L) Dorsal view of a 23 hour
embryo. Note that the staining is confined to the
left LPM. l, left; r, right. Image published in: Campione M et al. (1999) Copyright © 1999. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |