XB-IMG-131370
Xenbase Image ID: 131370
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Fig. 3. cmXnr2 blocks mesendoderm induction by activin protein. (A) cmXnr2
blocks animal cap elongation induced by activin protein. Animal caps explanted
from embryos injected with or without cmXnr2 RNA were dissected and treated
with 3 ng/ml of human activin A protein, and analyzed at stage 22. (B) cmXnr2
blocks mesendoderm induction by activin protein. RT-PCR analysis of stage 10.5
and stage 25 animal cap RNA for mesodermal (Xbra, chordin, Xlim-1, Xnr1 and
muscle actin) and endodermal (cerberus, Mixer, edd/endodermin, and XlHbox8)
markers. Note that induction of Xnr1 by activin protein is not blocked by cmXnr2. Image published in: Osada SI and Wright CV (1999) Copyright © 1999. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |