Xenbase Image ID: 131454

FIG. 2. Xenopus nodal related 1 (Xnr1) but not Xnr2 affects the asymmetric expression of BMP4 in the linear heart tube. (A) Section through the heart of a stage 34 embryo previously injected with XNR1 DNA mixed with b-galactosidase RNA into the dorsal right blastomere at the 4-cell stage and stained for BMP4 expression (purple) and b-gal activity (light blue). The blue arrow points at up-regulation of BMP4 expression on the right side of the linear heart. (B) Section through the heart of a stage 34 embryo previously injected with XNR2 DNA mixed with b-galactosidase RNA into the dorsal right blastomere at the 4-cell stage and stained for BMP4 expression (purple) and b-gal activity (light blue). The red arrow points at the unaffected BMP4 expression in the heart tube, which at this stage is predominantly on the left side. Image published in: Breckenridge RA et al. (2001) Copyright © 2001. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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