XB-IMG-131660
Xenbase Image ID: 131660
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Fig. 3. Expression of Xmsx-1 is specifically regulated by BMP-4.
(A) BMP-4 or activin RNA at the concentration indicated was injected
into dorsal two blastomeres at 4-cell stage, and dorsal marginal zone
(DMZ) tissues were excised at early gastrula (stage 10+). Total RNA
from 10-15 explants were subjected to RT-PCR analysis to detect
Xmsx-1 and EF-1a mRNAs. (B) The densitometric analysis was
performed with a scanning imager (Personal Densitometer, Molecular
Dynamics Japan, Tokyo, Japan). The relative density of each sample
was normalized by the densitometric values of uninjected DMZ
explants. Note that BMP-4, but not activin, was able to enhance the
expression of Xmsx-1 in a dose-dependent manner. Image published in: Maeda R et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |