Xenbase Image ID: 131662

Fig. 5. Morphological views of whole embryos injected with Xmsx-1 RNA. Dorsal two blastomeres at 4-cell stage were injected with capped Xmsx-1 RNA (5 ng/embryo), and these embryos (B,D,F) or control uninjected embryos (A,C,E) were allowed to develop to stage 35/36. The embryos injected with Xmsx-1 exhibit microcephaly with small eye capsules and swollen abdomens. Some embryos were immunostained with anti-N-CAM antibody, 4d (C,D) or with anti-notochord antibody, MZ-15 (E, F), showing significant reduction of both markers in injected embryos (D, F). Arrowhead in F shows a trace of notochord in Xmsx-1- injected embryo. Bar in A indicates 1 mm. Image published in: Maeda R et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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