XB-IMG-131666
Xenbase Image ID: 131666
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Fig. 9. The distinct ventralizing activities in inducing mesodermal
tissues raised by BMP-4 and Xmsx-1. Dorsal, lateral or ventral two
blastomeres at 4-cell stage were injected with Xmsx-1 or BMP-4 RNA
(5 ng /embryo), and dorsal/lateral/ventral marginal zone
(DMZ/LMZ/VMZ) tissues were excised at early gastrula (stage 10+)
for subsequent culture for 2 days. Total RNA from 10-15 explants
were extracted and 2 mg RNA was electrophoresed in each lane for
northern blot analysis to detect a-actin, a-globin and EF-1a. Note
that Xmsx-1 induced the expression of a-actin and inhibited the
expression of a-globin in VMZ explants. Image published in: Maeda R et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |