XB-IMG-131685
Xenbase Image ID: 131685
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Fig. 1. Construction of Xbra-GR. The hormone binding
domain of the human glucocorticoid receptor (hGR)
amino acids 512-777 was fused to the carboxy-terminus
of Xbra (1-432) to generate Xbra-GR. This fusion
replaces the stop codon of Xbra with two amino acids
(DL) generated by the insertion of a BglII site (see
Materials and methods). The DNA-binding and activation
domains of Xbra are shown by shaded and hatched
boxes, respectively (see Kispert and Herrmann, 1993;
Conlon et al., 1996). The hormone-binding domain of
hGR is shown by a solid box. Image published in: Tada M et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |