XB-IMG-131699
Xenbase Image ID: 131699
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Fig. 4. Analysis of convergent extension in exogastrulae and dorsal marginal zone explants. Stage 24 exogastrulae obtained from embryos
microinjected at 4-cell-stage into both dorsal blastomeres with DXotx1 (A) or Xotx1 (B) RNA and subsequently transferred in a hypertonic
solution. Whereas DXotx1 exogastrulae were indistinguishable from uninjected exogastrulae (A), Xotx1 injection yielded exogastrulae that
show a reduced elongation; in extreme cases (B, top row, leftmost embryo), strong inhibition of convergent extension gave rise to radially
symmetrical exogastrulae. Dorsal marginal zone explants isolated from stage 10 embryos microinjected at 4-cell-stage into both dorsal
blastomeres with DXotx1 (C) or Xotx1 (D) RNA and analyzed when control embryos reached stage 23. Morphogenetic movements of the dorsal
marginal zone appear to be inhibited by Xotx1 overexpression. Image published in: Andreazzoli M et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |