Xenbase Image ID: 131712

Fig. 9. Brat-EnR disrupts mesodermal patterning. (A) Vegetal view stage 11 wild-type embryo, positioned with the dorsal blastopore lip at the bottom. (B) Dorsal injection of Brat-EnR inhibits dorsal blastopore lip formation. (C) Ventrally injected embryo shows normal dorsal lip formation, but ventral lip formation is blocked. (D) Stage 35 wild-type embryo. (E) Embryos injected in the dorsal marginal zone with Brat- EnR mRNA do not develop anterior head structures (note the lack of eyes) and the neural plate does not close (arrow). (F) Ventral injection of Brat-EnR disrupts posterior mesoderm development, but anterior development is not affected. A total of 2 ng of Brat-EnR was injected into two dorsal or two ventral blastomeres at the 4-cell stage. Image published in: Horb ME and Thomsen GH (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

Return to previous page