XB-IMG-131825
Xenbase Image ID: 131825
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Fig. 5. ESR-1 expression is blocked by X-Su(H)1DBM. Test RNAs
(1.0 ng/embryo), as indicated above each lane, along with Noggin
RNA (0.3 ng/embryo) were injected into two-cell stage embryos, and
the induction of ESR-1 expression was measured in animal cap
assays as described in Fig. 3. (A) Expression of X-Delta-1 in
neuralized animal caps induces the expression of ESR-1 (compare
lanes 2 and 6). This induction is reduced by the inclusion of XSu(
H)1DBM (DBM) or X-Su(H)1 but not by X-Su(H)1-Tr, a carboxyterminally
truncated form of X-Su(H)1 (see Fig. 1B). Quantitation of
the ESR-1 signal in lanes 3-6 is: 91, 24, 24, and 60, respectively.
(B) Compilation of inhibition of X-Delta-1-mediated ESR-1
induction by X-Su(H)1 and X-Su(H)1DBM (DBM). The number of
data points is indicated (n=) and error bars indicate the true
population standard deviation. Image published in: Wettstein DA et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |