XB-IMG-131832
Xenbase Image ID: 131832
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Fig. 5. Distribution of Pax-6 mRNA in Xenopus embryos. A-G show anterior views, H is a dorsal
view with the anterior end of the embryo to the left, and I is a lateral view. (A) A st. 12 embryo; note
a single band of expression continuous from one side of the embryo to the other in the anterior neural
plate (indicated by the red arrow) whereas there are two broad stripes of expression in the
primordium of the neural tube (indicated by the red arrowhead). (B) A st. 12.5 embryo. The stripes in
the trunk region are thinner and closer to each other than those at st. 12. Note the appearance of lens
primordia on each side of the embryo (indicated by the green arrow). (C) A st. 16 embryo. The two
red lines demarcate the borders of the retina stripe. The arrow points to a lens primordium. Pax-6
expression has three components: lens primordium, an outer semicircle of the retina field and an
inner semicircle of a forebrain structure. The forebrain stripe later resolves into two spots posterior to
the eyes shown in D and G, which are the two spots closer to the midline than the eyes in E and F.
(D) A st. 18 embryo showing that Pax-6 expression in the median region of the anterior neural plate
is turned off. The red line indicates the border between the eye primordium and the forebrain
structure. Note also that the lens primordia have moved into the retina primordia to form the eye
primordium by this stage (compare D to C). (E) A st. 19 embryo showing distinct Pax 6 expression
in the eyes and the forebrain. (F) A stage 26 embryo. (G) Higher magnification of a st. 18 embryo.
The line points to the border between the forebrain staining and the eye staining. (H) Dorsal view of
a st. 24 embryo showing Pax-6 expression in the neural tube derived from the two broad stripes in
the trunk region at st. 12 (the arrowhead in A). (I) A st. 25 embryo. Compare Pax-6 expression in the
entire eye to ET expression in only the dorsal retina in Fig. 3H. Image published in: Li H et al. (1997) Copyright © 1997. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |