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Fig. 4. Zygotic b-catenin mRNA is synthesized from the early gastrula stage onwards. Maternal b-catenin was depleted from oocytes by injection of antisense oligo, and then oocytes and embryos derived from the same batch of oocytes were frozen at the stages shown. The developmental northern blot was probed with a b-catenin probe and with Ef1a as a loading control. +, uninjected; -, depleted of maternal b-catenin mRNA. Zygotic b- catenin mRNA has appeared by stage 10 (early gastrula), and reaches wild-type levels during gastrulation.

Image published in: Wylie C et al. (1996)

Copyright © 1996. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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