Xenbase Image ID: 132022

Fig. 13. Xom inhibits induction of dorsal mesoderm by activin but does not affect activation of Xbra or induce expression of aT4 globin. Animal caps derived from embryos injected with RNA encoding Xom or DXom were exposed, where appropriate, to activin (4 units/ml) and cultured to the equivalent of stage 25 for analysis of cardiac actin expression, to stage 10.5 for analysis of Xbra and to stage 25 for analysis of aT4 globin. (A) Induction of cardiac (muscle-specific) actin is inhibited by Xom RNA but not by DXom. (B) Expression of Xbra is not affected by Xom and Xom does not induce expression of aT4 globin, even though activin-induced elongation in this experiment was blocked (not shown). Expression of EF-1a was used as a loading control. Image published in: Ladher R et al. (1996) Copyright © 1996. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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