XB-IMG-132174
Xenbase Image ID: 132174
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FIG. 1. Comparison of Xbra3 with other T-domain proteins. (A) Alignment of the predicted polypeptide sequence of Xbra3 with Xbra
(Smith et al., 1991), mouse Brachyury (Mo T; Herrmann et al., 1990), human T (Hu T; Edwards et al., 1996), chick T (Ch T; Kispert et al.,
1995), chick T-box T (Ch TbxT; Knezevic et al., 1997) and zebrafish no-tail (Zf ntl; Schulte-Merker et al., 1994). Dashes have been inserted
to introduce gaps to maximise the alignment. An antiserum specific for Xbra3 was raised against a peptide representing residues 420–431
(overlined). (B) Dendrogram of T-box genes produced by the PHYLIP program. Sequences and SwissProt accession numbers (except where
indicated) are Brachyury (P20293), human T (Hu-T; translated from GenBank; AJ001699), chicken T-box T (TbxT; P79778), Halocynthia
T (As-T; P56158), chicken T (Ch-T; P79777), Drosophila T-related gene (Trg; P55965), Xenopus Brachyury (Xbra; P24781), Xenopus
Brachyury 3 (Xbra3; this work), Hemicentrotus T (Hp-T; Q25113), zebrafish T (Zf-T; Q07998), Xenopus Eomesodermin (Eomes; P79944),
Xenopus Xombi (Xombi; translated from GenBank; S83518), Xenopus Brat (Brat; P87377), chicken T-box L (TbxL; P79779), human T-box
5 (Hu-Tbx5; Q99593), human T-box 3 (Hu-Tbx3; translated from GenBank; AF002228) and Ascidian T (As-T2; O01409; also from
Hemicentrotus). Image published in: Strong CF et al. (2000) Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View |