Xenbase Image ID: 132184

FIG. 5. Ectopically expressed pMesogenin1 suppresses dorsal mesoderm formation. pMesogenin1 RNA (4 ng per embryo) was injected into either the dorsal (DMZ) or the ventral (VMZ) marginal zone of four-cell stage blastomeres, and expression of the dorsal marker Chordin (A, B, and C) and ventrolateral mesodermal marker Xwnt-8 (D, E, and F) was analyzed by whole-mount in situ hybridization. (G) Morphological defects in the tadpoles injected in the DMZ of four-cell stage embryos with pMesogenin1. Tadpoles showing more severe defects are arranged from top to bottom. pMesogenin1 caused a failure of axis extension, probably due to the defect in dorsal structure formation. Image published in: Yoon JK et al. (2000) Copyright © 2000. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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