Xenbase Image ID: 132507

FIG. 6. Homologies with other vertebrate rhodopsin upstream sequences. A, proximal sequence homology. Sequence alignment of the ;450 immediate upstream nucleotides of the Xenopus (XEN), chicken (CHK), human (HUM), bovine (BOV), rat (RAT), and mouse (MUS) rhodopsin genes is shown. Alignments were created using a window size of 6 and a stringency of 67%. Gaps introduced in the sequence for optimal alignment are shown by dots. Regions containing greater than 75% identity across species are shaded. Transcription start sites (boxed nucleotides) and position of the initiator methionine (arrow) are indicated. Potential GC boxes binding SP1 are indicated with dotted underline and pyrimidine tracts with solid underline. B, nucleotide identities of the Xenopus upstream sequence with glass elements, proximal and distal, with core sequences underlined. Nucleotides conserved between Xenopus and chicken are shown in italics, and across all three species are indicated in bold. C, homologies of the Xenopus rhodopsin upstream sequence with the human retinal leucine zipper binding sequence, NRL, and rat Ret2 are shown with nucleotide identities in bold. Image published in: Batni S et al. (1996) Copyright © 1996. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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