Xenbase Image ID: 132735

Fig. 1. Identification of the premigratory neural crest transcriptome signature during neurulation (A) Several types of early embryo explants were dissected for microarray analysis: the animal cap ectoderm, cut at blastula stage 9 and allowed to develop until stage 14 in vitro (AC14), the early neural plate at stage 12 (NP12), the lateral neural border at stage 14 (NB14), the premigratory cranial neural crest and its overlying ectoderm at stage 18 (NB18), and the anterior neural fold at stage 18 (ANF18). Expression level thresholding, differential analysis, and clustering defined a group of 83 genes enriched in neural border samples. (B) Outline of the experimental strategy used to identify the neural crest transcriptome signature. Image published in: Plouhinec JL et al. (2014) Copyright © 2014. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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