Xenbase Image ID: 132958

FIG. 3. Pcl1 effects on brain and eye markers. Control (b-galactosidase) or mPcl1 RNA was injected bilaterally into the dorsal marginal zone of four-cell-stage embryos. Expression of N-CAM (pan-neural), Rx2A (eye), Xotx2 (eye, forebrain, midbrain), X-dll3 (forebrain, otic vesicle, branchial arches, cement gland), and Xwnt8-b (forebrain–midbrain boundary) was assayed by whole-mount RNA in situ hybridization. Representative embryos are shown from Stage 19–22 (left) and Stage 26 (right). Developing eye field is denoted by arrowheads, and forebrain-specific gene expression is denoted by arrows. Note that neural patterning is unchanged at Stage 19–22, even when eye markers are completely absent. Image published in: Yoshitake Y et al. (1999) Copyright © 1999. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue ncam1.S n-cam, n-cam-1, ncam, ncam1-a, ncam1-b X. laevis Sometime during NF stage 19 to NF stage 22 optic vesicle neural tube ncam1.S n-cam, n-cam-1, ncam, ncam1-a, ncam1-b X. laevis Throughout NF stage 26 central nervous system brain spinal cord forebrain midbrain hindbrain rax.S rax-a, rax-b, rax1, rx, rx-1, rx1, rx1a, Rx2A, Xrax, Xrx1, Xrx1A X. laevis Sometime during NF stage 19 to NF stage 22 eye primordium optic vesicle rax.S rax-a, rax-b, rax1, rx, rx-1, rx1, rx1a, Rx2A, Xrax, Xrx1, Xrx1A X. laevis Throughout NF stage 26 eye optic vesicle otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Sometime during NF stage 19 to NF stage 22 forebrain midbrain eye otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 26 midbrain eye optic vesicle dlx5.L dll3, X-dll3 X. laevis Sometime during NF stage 19 to NF stage 22 cement gland primordium anterior neural fold otic placode dlx5.L dll3, X-dll3 X. laevis Throughout NF stage 26 pharyngeal arch otic placode forebrain cement gland primordium wnt8b.S LOC108696239, wnt-8b, Xwnt-8b, xwnt8b X. laevis Sometime during NF stage 19 to NF stage 26 pretectum Image source: Published Larger Image Printer Friendly View

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