Xenbase Image ID: 133063

Fig 3. Caspase-3 activity in the tadpole tails in the 2-wk assay and retention of muscle in tail tip. (a) Tail from a wild-type animal treated with 10 nM T3 for 4 days. Note the caspase-3-positive muscle fibers (examples are shown with arrowheads). (b) Tail from an untreated control animal. (c) Tail from a pCar/TRDNα-expressing animal treated with 10 nM T3 for 4 days. Note the caspase-3-positive epidermal cells similar to a but the lack of caspase-positive muscle fibers. (d–f) Tips of the tail stained with MF20 (red) and anti-active caspase-3 antibody (green) of 10 nM T3-treated (7 days) wild-type, untreated wild-type, and 10 nM T3-treated (7 days) pCar/TRDNα tadpoles, respectively. [Bars = 100 μm (a–c) and 200 μm (d–f).] Image published in: Das B et al. (2002) Copyright © 2002. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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