Xenbase Image ID: 133229

Figure 3. Molecular characterization of the developing Xenopus foregut and respiratory epithelium. A: Schematic of the developing foregut region and respiratory system at the indicated developmental stages, with endoderm in yellow, heart (h) in orange, and respiratory epithelium in blue. B–Y: Whole-mount in situ hybridization with the indicated probes to whole embryos at NF32 (B,F,J), NF33 (N), NF35 (R), NF38 (V) or to isolated guts at NF42 (C,G,K,O,S,W) or to lung/tracheal/esophageal regions dissected at NF49 (D,H,L,P,T,X) or NF59 (E,I,M,Q,U,Y). Abbreviations: e, esophagus; fg, foregut; h, heart; lb, lung bud; lg, lung; lv, liver; st, stomach; tr, trachea; ty, thyroid. Scale bar = 0.5 mmDownload figure to PowerPoint Image published in: Rankin SA et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, John Wiley & Sons. Gene Synonyms Species Stage(s) Tissue foxa2.L HNF-3B, hnf3-beta, hnf3b, hnf3beta, LOC108717763 X. laevis Throughout NF stage 32 endoderm foregut spinal cord head head endoderm foxa2.L HNF-3B, hnf3-beta, hnf3b, hnf3beta, LOC108717763 X. laevis Throughout NF stage 42 endoderm foregut esophagus liver trachea lung primordium foxa2.L HNF-3B, hnf3-beta, hnf3b, hnf3beta, LOC108717763 X. laevis Throughout NF stage 49 endoderm trachea lung foregut esophagus stomach foxa2.L HNF-3B, hnf3-beta, hnf3b, hnf3beta, LOC108717763 X. laevis Throughout NF stage 59 respiratory system endoderm trachea lung foregut epithelial cell shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 32 endoderm foregut head brain pharyngeal arch eye liver diverticulum notochord shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 42 endoderm foregut lung primordium liver primordium shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 49 endoderm trachea foregut lung primordium esophagus stomach shh.L hedgehog, vhh-1, X-SHH, Xhh, xshh X. laevis Throughout NF stage 59 trachea lung esophagus sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 32 endoderm foregut head brain eye lateral line ganglion sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 42 endoderm trachea foregut lung primordium sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 49 endoderm trachea foregut lung primordium esophagus sox2.L anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 59 lung primordium nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Throughout NF stage 33 and 34 endoderm foregut lung primordium thyroid primordium eye brain forebrain nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Throughout NF stage 42 endoderm trachea foregut lung primordium nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Throughout NF stage 49 endoderm trachea foregut lung primordium nkx2-1.L nkx2.1, titf1, ttf1, Xnkx-2.1, xnkx2-1 X. laevis Throughout NF stage 59 endoderm trachea lung foregut lung primordium sox9.S cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 X. laevis Throughout NF stage 35 and 36 head brain eye pharyngeal region notochord sox9.S cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 X. laevis Throughout NF stage 42 endoderm foregut lung primordium sox9.S cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 X. laevis Throughout NF stage 49 endoderm trachea lung foregut esophagus sox9.S cmd1, cmpd1, sox-9, sox9-a, sox9-b, sra1 X. laevis Throughout NF stage 59 endoderm trachea lung foregut esophagus sftpc.S SP-C, SPC, surfc, xSP-C X. laevis Throughout NF stage 37 and 38 endoderm foregut epithelial cell lung primordium sftpc.S SP-C, SPC, surfc, xSP-C X. laevis Throughout NF stage 42 endoderm trachea lung foregut epithelial cell sftpc.S SP-C, SPC, surfc, xSP-C X. laevis Throughout NF stage 49 endoderm trachea lung foregut epithelial cell sftpc.S SP-C, SPC, surfc, xSP-C X. laevis Throughout NF stage 59 endoderm trachea lung foregut epithelial cell Image source: Published Larger Image Printer Friendly View

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