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XB-IMG-133342

Xenbase Image ID: 133342

Fig. 7. Comparison of a short sequence found in the Xcat-2 protein and selected proteins that interact with nucleic acids. A 10 amino acid stretch in Xcat-2 showed identity with 7 amino acids (9 allowing conserved substitutions) with a region in histone H1 located within the DNA-binding loop. A search of protein sequence banks revealed a short list of other proteins 70% identical with this region; none were completely identical. Many of these proteins interact with nucleic acids or nucleotides. Selected examples of such proteins are listed. Amino acids identical to the Xcat-2 region are boxed, conserved substitutions are marked with a black dot. The histone H1 sequence is identical in cow, human, rabbit, chicken, mouse and rat (Allan et al., 1980). DpnI is a restriction enzyme, endonuclease from Streptococcus pneumonia. Also listed are AT-BP1, a zinc finger protein found in rats (Mitchelmore et al., 1991); EF-Tu, an elongation factor (Jurnak, 1985); LCVLA L protein, a RNA-dependent RNA polymerase (Singh et al., 1987); NADH dehydrogenase (ubiquinone).

Image published in: Mosquera L et al. (1993)

Copyright © 1993. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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