Xenbase Image ID: 133364

Figure 6. Overexpression of xBMAL1 or xNOCTURNIN protein results in larger, disorganized somites with disrupted somite boundaries. Panel A represents the results of analyzing paired somite area (uninjected side vs injected) using NIH Image J. The average ratio of the area of injected to uninjected sides of the embryos analyzed is shown with error bars representing standard deviation. A significant difference in area between 150 pg xBmal1 RNA injection (*; p<0.02) and 500 pg xNocturnin RNA injection was observed (*; ANOVA posthoc LSD compared to control MO, p<0.009). Panels B-G compare muscle actin (12/101) of the uninjected (B, C, F) and injected sides (D, E, G) of embryos overexpressing xBMAL1 (D, 500 pg; G, 150 pg) or xNOCTURNIN (E, 500 pg). All images were taken at the same magnification (scale bar = 10 µm). doi:10.1371/journal.pone.0108266.g006 Image published in: Curran KL et al. (2014) Image reproduced on Xenbase with permission of the publisher and the copyright holder. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

Return to previous page