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FIGURE 5. Xdpcp acts upstream of Smad2. A, RT-PCR analysis revealing that Xdpcp cannot inhibit the expression of mesendodermal markers induced by CA-Smad2 in animal cap tissues. WE and −RT, control RT-PCR on the whole embryo RNA in the presence or absence of reverse transcriptase; AC, uninjected animal cap cells; (−), the animal cap cells injected with CA-Smad2 RNA alone. Ornithine decarboxylase (ODC) serves as a loading control. B, the morphological defects by xdpcp overexpression are partially rescued by CA-Smad2. C, the graph showing the results of panel B.

Image published in: Cheong SM et al. (2009)

Copyright © 2009. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

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