Xenbase Image ID: 133543

Fig. 6. Distinct effects of expression of N and DN-C in Xenopus embryos. Uninjected embryos (WT), and embryos injected with N, or DN-C were photographed at tadpole stage (A) or analyzed by in situ hybridization (B, C). (A) Cement glands (arrow) and other anterior structures are enlarged in N-injected embryos. In contrast, embryos injected with DN-C display a smaller cement gland, reduced anterior structures, and enhanced posterior structures. (B) In situ hybridization was performed with a pan neural RNP marker. Arrows indicate the otic vesicle. The neural tissue anterior to the otic vesicle is enlarged in N-injected embryos, and reduced in DN-Cinjected embryos as compared to control embryos. (C) In situ hybridization was performed with the forebrain marker Otx-A. The pattern of Otx-A expression (arrows) is expanded in N-injected embryos while expression in DN-C-injected embryos is similar, but reduced in comparison to that of control embryos. Image published in: Lai CJ et al. (1995) Copyright © 1995. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue otx2.S otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 29 and 30 forebrain midbrain nrp1.L A5 antigen, LOC108718763, neuropilin, neuropilin-1, np-1, npn-1, nrp, nrp-1, pNPG152 X. laevis Throughout NF stage 29 and 30 central nervous system brain spinal cord eye otic vesicle cranial ganglion cranial nerve Image source: Published Larger Image Printer Friendly View

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