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Figure 6 Normal and reduced expression of mRNAs cod- ing for Pax6 and the cell adhesion molecules mNcad, Ncad or NCAM. A: Normal expression during development (Stage 1– 38). Relative mRNA levels are normalized to 18S rRNA. B: Average mRNA levels of Pax6 (n 1⁄4 7 batches of 5 embryos each), mNcad (n 1⁄4 12), Ncad (n 1⁄4 6) and NCAM (n 1⁄4 9) in Pax6 knockdown embryos at Stage 32. The respective mRNA levels are given as ratio over that of sibling control embryos. For statistical significance see text. C: Expression of mNcad mRNA in control (MO CO) and Pax6 knockdown (MO Pax6) embryos during development. Average of 5 independent ex- perimental series. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

Image published in: Rungger-Brändle E et al. (2010)

Copyright © 2010. Image reproduced with permission of the Publisher, John Wiley & Sons.

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