Xenbase Image ID: 133746

Fig. 1. Expression screen for direct transcriptional targets of Wnt signaling in neural tissue. (A) X. tropicalis embryos stained for transcripts identified as Wnt targets by RNA-seq. Stage 10.5 embryos show dorsovegetal views with the dorsal lip toward the top. Stage 12 and 15 embryos show dorsal views with anterior toward the top. (B,C) qPCR on 15-25 animal caps treated as indicated on the x-axis. The y-axis shows expression relative to odc. n=4 experiments. (D) Luciferase reporter assays in HEK293 cells treated with or without mouse Fgf. n=3 experiments. Error bars indicate s.e.m. All means were compared by one-way ANOVA followed by Tukey post-hoc analyses (*P<0.05). Image published in: Young JJ et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue sf3b4.S spx X. laevis Throughout NF stage 10.5 ectoderm dorsal sf3b4.S spx X. laevis Throughout NF stage 12 ectoderm neuroectoderm dorsal sf3b4.S spx X. laevis Throughout NF stage 15 neural plate neuroectoderm hnrnpk.S X. laevis Throughout NF stage 10.5 ectoderm dorsal marginal zone hnrnpk.S X. laevis Throughout NF stage 12 circumblastoporal collar hnrnpk.S X. laevis Throughout NF stage 15 neural plate neuroectoderm neural groove circumblastoporal collar prickle1.S prickle, prickle A, prickle B, Prickle-b, prickle1-a, prickle1-b, XPk, XPk-1 X. laevis Throughout NF stage 10.5 marginal zone prickle1.S prickle, prickle A, prickle B, Prickle-b, prickle1-a, prickle1-b, XPk, XPk-1 X. laevis Throughout NF stage 12 neural plate neuroectoderm neural groove circumblastoporal collar prickle1.S prickle, prickle A, prickle B, Prickle-b, prickle1-a, prickle1-b, XPk, XPk-1 X. laevis Throughout NF stage 15 neural plate neuroectoderm circumblastoporal collar neural groove sall1.L LOC108715370, sal-1, sal-like 1, sal1, sall1-a, sall1-b, sall1b, spalt-like 1, tbs, znf794 X. laevis Throughout NF stage 10.5 dorso-lateral marginal zone ectoderm mesoderm involuted dorsal mesoderm sall1.L LOC108715370, sal-1, sal-like 1, sal1, sall1-a, sall1-b, sall1b, spalt-like 1, tbs, znf794 X. laevis Throughout NF stage 12 circumblastoporal collar posterior neuroectoderm neural plate sall1.L LOC108715370, sal-1, sal-like 1, sal1, sall1-a, sall1-b, sall1b, spalt-like 1, tbs, znf794 X. laevis Throughout NF stage 15 neural groove posterior neuroectoderm circumblastoporal collar sall4.L drrs, znf797 X. laevis Throughout NF stage 10.5 ectoderm marginal zone sall4.L drrs, znf797 X. laevis Throughout NF stage 12 neural plate neuroectoderm chordal neural plate circumblastoporal collar sall4.L drrs, znf797 X. laevis Throughout NF stage 15 neural plate neuroectoderm neural groove circumblastoporal collar srsf7.L 9g8, aag3, sfrs7 X. laevis Throughout NF stage 10.5 ectoderm dorso-lateral marginal zone srsf7.L 9g8, aag3, sfrs7 X. laevis Throughout NF stage 12 neural plate neuroectoderm srsf7.L 9g8, aag3, sfrs7 X. laevis Throughout NF stage 15 neural plate neuroectoderm chordal neural plate Image source: Published Larger Image Printer Friendly View

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