Xenbase Image ID: 133752

Fig. 7. Overexpression of pou5f3 represses neural differentiation. Whole-mount in situ hybridization of (A,C,E,G) uninjected control embryos and (B,D,F,H) embryos injected with 150 pg pou5f3 RNA (50 pg each of pou5f3.2, pou5f3.3 and pou5f3.1 RNAs) into the right A/D blastomere. Red staining is β-galactosidase used as a tracer for RNA injection. (C′-F′) Higher magnification views of the boxed regions in C-F. (A-D) otx2, krox20 and hoxb9 expression in anterior (A,B) or dorsal (C,D) view. (E-H) hoxc10 (E,F) and sox2 (G,H) expression in dorsal view. Image published in: Young JJ et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue otx2.L otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 18 optic vesicle eye primordium anterior placodal area neural plate pre-chordal neural plate egr2.L EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. laevis Throughout NF stage 18 presumptive rhombomere neural crest premigratory neural crest cell hoxb9.L hox 2.5, xhoxb9, XlHbox-6, XlHbox6 X. laevis Throughout NF stage 18 presomitic mesoderm rostral presomitic mesoderm caudal presomitic mesoderm hoxc10.L LOC108709895, MGC80182, XHoxc10 X. laevis Throughout NF stage 18 presomitic mesoderm caudal presomitic mesoderm sox2.S anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 18 neural plate pre-chordal neural plate chordal neural plate neural groove anterior placodal area Image source: Published Larger Image Printer Friendly View

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