Xenbase Image ID: 133754

Fig. 9. Fgf and RA signaling fail to posteriorize Sall4 morphants. Whole-mount in situ hybridization of (A,E) uninjected control embryos, (B,F) embryos injected with 40 ng Sall4 MO (20 ng/blastomere at the 2-cell stage), (C,G) embryos injected with 50 pg fgf8a RNA into the right A/D blastomere, (D,H) embryos injected with 40 ng Sall4 MO (20 ng/blastomere at the 2-cell stage) and 50 pg fgf8a RNA into the right A/D blastomere, (I,K) embryos treated with 1 μM all-trans retinoic acid (ATRA) and (J,L) embryos injected with 40 ng Sall4 MO (20 ng/blastomere at the 2-cell stage) and treated with 1 μM ATRA. Expression is shown for (A-D,I,J) otx2, krox20 and hoxb9 or (E-H,K,L) sox2. Arrowheads indicate the posterior limit of otx2 expression. Dorsal views, anterior to the top. Image published in: Young JJ et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue otx2.L otx-2, otx2-a, otx2-b, otxA, Xotx-2, Xotx2 X. laevis Throughout NF stage 18 eye primordium optic vesicle neural plate pre-chordal neural plate anterior placodal area egr2.L EGR-2, Krox-20, krox20, XKr20, XKrox-20 X. laevis Throughout NF stage 18 presumptive rhombomere hoxb9.L hox 2.5, xhoxb9, XlHbox-6, XlHbox6 X. laevis Throughout NF stage 18 presomitic mesoderm caudal presomitic mesoderm sox2.S anop3, LOC108718087, mcops3, Sox-2, XLSOX-2, Xsox-2, XSox2 X. laevis Throughout NF stage 18 neural plate pre-chordal neural plate chordal neural plate neural tube anterior neural tube posterior neural tube anterior placodal area Image source: Published Larger Image Printer Friendly View

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