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XB-IMG-134358

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Fig. 3. Morpholino antisense oligonucleotides efficiently disrupt target protein translation. Side by side comparison of Xenopus laevis embryos injected with 5׳UTR-GFP mRNA (left column) and targeted morpholino versus 5׳UTR-GFP mRNA and control morpholino (right column). (A) Embryos injected with either control or targeted FITC labeled morpholinos. (B–F) X. laevis embryos stained with anti-GFP antibody show abundance of GFP in embryos injected with control morpholino, while targeted morpholino efficiently prevents mRNA translation and GFP protein production.

Image published in: Uy BR et al. (2015)

Copyright © 2015. Image reproduced with permission of the Publisher, Elsevier B. V.

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