Xenbase Image ID: 134794

Fig. 7. The putative Shp2-binding sites, but not the putative Grb2-binding sites, are important for XFrs3 function during eye development. Indicated combinations of XFrs3 MO or random (Ran.) MO (7.5 pmole each/embryo) along with wild type (WT) or mutant (4YF, 2YF, or 6YF) XFrs3 mRNA (50 pg each/embryo) were injected into equatorial region of 2-cell embryos. (A) Embryos are scored for phenotypes at stage 38. The percentages of embryos with microphthalmia or anophthalmia are tabulated in the bottom panel. Injections were carried out with 3 separate batches of embryos. (B) Embryos, scored for particular phenotypes in panel A, were sectioned at the level of eyes and stained with hematoxylin/eosin. Image published in: Kim YJ et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, Elsevier B. V. Larger Image Printer Friendly View

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