Xenbase Image ID: 135036

Fig. 1. Sequence of Xwnt-11 and comparison with other Xwnt genes. (A) The nucleotide sequence of Xwnt-11 is shown, with the amino acid sequence underneath. Numbers in bold refer to the amino acid sequence. (B) Amino acid sequence comparisons are shown for Xwnt-1, Xwnt-4, Xwnt-8 and Xwnt-11, for which complete coding region sequence is known. Cysteines that are conserved between all other known mouse wnt genes are printed in bold. Potential N-linked glycosylation sites are underlined in the Xwnt-11 sequence. The regions to which degenerate PCR primers were made are indicated by double underlining. The asterisks mark the end of the coding region. (C) Amino acid sequence similarities are compared between Xwnt-1, Xwnt-4, Xwnt-8 and Xwnt-11. The numbers above the diagonal are absolute amino acid similiarities, and the numbers below the diagonal include conserved amino acid substitutions (serine-threonine, isoleucineleucine- methionine-valine, glutamic acidaspartic acid, glutamine-asparagine and lysine-arginine). Image published in: Ku M and Melton DA (1993) Copyright © 1993. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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