XB-IMG-135048
Xenbase Image ID: 135048
|
Fig. 1. Sequence of a Xenopus MHCa cDNA fragment.
(A) Nucleotide sequence of a Xenopus MHC cDNA fragment
isolated from adult heart cDNA. The sequence is derived from
two overlapping clones obtained by RT-PCR (see Methods) and
has been submitted to the EMBL database. The encoded
polypeptide fragment is shown along with the termination codon
(*) and putative polyadenylation signal (underlined).
(B) Alignment of the Xenopus MHC polypeptide sequence with
the carboxy terminal region of other vertebrate MHC sequences.
The XMHCa sequence most closely resembles the human
(Yamauchi-Takihara et al., 1989), mouse (EMBL accession
number M74751), rat (McNally et al., 1989), rabbit (Sinha et al.,
1984) and hamster (Liew and Jandreski, 1986) MHCa proteins in
the final seven residues. The human (Yamauchi-Takihara et al.,
1989), mouse (EMBL accession number M74752), rat (Kraft et
al., 1989) and hamster (Jandreski et al., 1988) MHCb isoforms are
also shown, along with the b-like newt MHCc/s (Casimir et al.,
1988) and the cardiac-specific chick VMHC1 (Bisaha and Bader,
1991) sequences. Image published in: Logan M and Mohun T (1993) Copyright © 1993. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |