Xenbase Image ID: 135060

Fig. 6. GATA-4 is an early marker for the developing heart. Embryos were analyzed by whole-mount in situ hybridization for GATA-4 RNA. Stages are as follows: 18 (A,B); 26 (C,D); 34 (E,F); 40 (G,H). The photographs shown in B,D,F and H are high magnification views of the embryos shown in A,C,E and G, respectively. Arrows indicate detection of GATA-4 message by alkaline phosphatase staining in the region of the developing heart; non-specific staining around the residual blastocoel (for example, in A) is seen with control sense-strand probes. Note that by stage 40, GATA-4 message is detected in other organs where transcription is high in adults, such as the stomach. In all cases, dorsal is towards the top. In C and D, anterior is to the left, otherwise anterior is to the right. Large arrows in F and H indicate staining in the developing heart (h). For reference, cg indicates the position of the cement gland. Image published in: Kelley C et al. (1993) Copyright © 1993. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue gata5.S gata-4a, GATA-5, gata5-a, gata5-b, xGATA-5, xGATA-5a, xGATA-5b, xGATA5, xGATA5a, xGATA5b X. laevis Sometime during NF stage 18 to NF stage 40 heart Image source: Published Larger Image Printer Friendly View

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