XB-IMG-135161
Xenbase Image ID: 135161
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Fig. 1. GRNs in the Xenopus mesoderm specification. (A) Marginal region of pregastrula stage embryo. The yellow area with mesh indicates the dorsal mesoderm, and the yellow area indicates the ventral marginal zone. The colored arrows and barreled lines indicate direct activation and repression of the target gene. All suspected indirect relationships have been excluded from the diagram. Transcription factors mediating growth factor signaling are indicated in boxes. Note that, in the dorsal mesoderm, Gsc and Xbra are coexpressed. (B) Marginal region of early-late gastrula stage embryo. During this period, the mesoderm is subdivided to become the dorsal (pink area), dorsolateral (hatched area), and ventrolateral mesoderm (yellow). All necessary primary references that support the arrows (direct interaction) are listed in Table 1, under “direct target genes.” The question marks denote direct activin/nodal or Wnt target genes. However, the transcription factors responsible for the induction are unknown. Image published in: Koide T et al. (2005) Copyright © 2005. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |