Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Xenbase Image ID: 135563

Fig. 5. Rarγ2 mRNA rescues posterior Hox and PSM expression in Rarγ2 MO embryos. (A-H) Embryos injected unilaterally at 2- or 4-cell stage. Injected side is indicated by magenta β-gal lineage tracer. (A,E) 5 ng Rarγ2.1 MO+5 ng Rarγ2.2 MO+control (mCherry) mRNA diminishes Hoxc10 and Msgn1 expression, curving the embryo axis in 100% of embryos (Hoxc10, 23/23; Msgn1, 13/13). (B,C,F,G) Co-injection of Rarγ2 MO and 1 ng Rarα2 mRNA or 1 ng Rarβ2 does not rescue the phenotype; however, (D,H) 1 ng Rarγ2 mRNA partially rescues axial curvature and Hoxc10 (18/23) and Msgn1 (23/35) expression. Tailbud embryos shown in dorsal view with anterior to left.

Image published in: Janesick A et al. (2014)

Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

Larger Image
Printer Friendly View

Return to previous page
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.0

Major funding for Xenbase is provided by grant P41 HD064556