Xenbase Image ID: 135566

Fig. 8. Overexpression of DN-Rarγ2 mRNA expands expression of PSM and CNH markers, shifting or knocking down somitomere markers Thyl2 and Ripply2. (A-J) Embryos injected unilaterally at 2- or 4-cell stage. Injected side is indicated by magenta β-gal lineage tracer. (A,C,E,G,I) Control (mCherry) mRNA does not alter expression of Tbx6, Msgn1, Thyl2, Ripply2 or xNot. (B,D,F) 2 ng DN-Rarγ2 mRNA expands expression of Msgn1 (8/11) and Tbx6 (15/23) (green lines) and rostrally shifts xNot (8/10). (H,J) DN-Rarγ2 overexpression produces multiple phenotypes of Thyl2 and Ripply2 expression, as characterized and scored in K. Neurula embryos shown in dorsal view with anterior to left. Image published in: Janesick A et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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