XB-IMG-135668
Xenbase Image ID: 135668
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Expression of ESR-4 and ESR-5during segmentation depends on the Notch signaling pathway. Embryos were injected on one side with RNAs encoding X-Delta-2(A,B), X-Su(H)–DBM (C– F), or X-Su(H)–Ank (G–J), and processed for expression of ESR-4(C,D,G,H) or for ESR-5 (A,B,E,F,I,J). A representative embryo from each injection is shown with a view of the uninjected or injected side. (A,B) Note that when embryos ectopically express X-Delta-2, expression of ESR-5 in the TZ increases (B, arrow). X-Su(H)–DBM completely blocksESR-4 expression (D, arrow) while significantly reducing ESR-5 expression in the somitomeric and TZ region (F, arrow). X-Su(H)–Ank expands the expression of bothESR-4 (H) and ESR-5 (J, arrow). The asterisk in H marks ectopic induction of ESR-4expression in the neural tube by X-Su(H)–Ank. Image published in: Jen WC et al. (1999) Copyright © 1999. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Larger Image Printer Friendly View |