Xenbase Image ID: 135670

CHX and TSA treatment rapidly alter the segmental expression of ESR-5, X-Delta-2, andThylacine1. Xenopus embryos at early neurulae stages were left untreated (A,E,I), or treated for 1 hr (B,F,J) or 2 hr (C,G,K) with CHX, or for 2.0 hr with TSA (D,H,L). Embryos were then fixed and stained forESR-5 expression (A–D), X-Delta-2expression (E–H) or for Thylacine1 expression (I–L). A side, posterior view of the stained embryos is shown. Note that following 1 hr of CHX treatment, ESR-5,X-Delta-2, and Thylacine1 expression changes by upregulating in the TZ (asterisks), whereas the striped expression ofX-Delta-2, Thylacine1, and ESR-5 in the somitomeric region is relatively unaffected. Similar effects on the expression of these genes in the TZ also occur after 2.0 hr of TSA treatment. Image published in: Jen WC et al. (1999) Copyright © 1999. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Larger Image Printer Friendly View

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