Xenbase Image ID: 135679

FIG. 5. xWT1 expression disrupts early events in pronephric specification. Expression of Xlim-1, an early molecular marker for the pronephros, was detected at stage 20 by in situ hybridization (dark purple in all panels) and b-galactosidase was detected with X-Gal (light blue/green in B and D). (A and B) Opposite sides of an embryo injected on one side with of b-galactosidase mRNA. Xlim-1 expression is strong on both the uninjected (A) and injected (B) sides. (C and D) Opposite sides of an embryo injected on one side with xWT1-KTS (1b-galactosidase mRNA). Xlim-1 expression is normal on the uninjected side (C), while expression is dramatically reduced on the injected side (D). The result indicates that ectopic xWT1 mRNA expression inhibits pronephric development at a very early stage. Image published in: Wallingford JB et al. (1998) Copyright © 1998. Image reproduced with permission of the Publisher, Elsevier B. V. Gene Synonyms Species Stage(s) Tissue lhx1.L lim-1, Lim1, lim1, Xlim-1, Xlim1 X. laevis Throughout NF stage 20 pronephric mesenchyme intermediate mesoderm Image source: Published Larger Image Printer Friendly View

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