XB-IMG-135738
Xenbase Image ID: 135738
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Figure 5. mWnt8, but not Noggin, represses Bmp4
expression during gastrulation. Ectoderm was injected
with 250pg of mWnt8 (A,E,I,M) or 100 pg of
noggin (B,F,J,N), aged to stage 10 (A–C), stage 10.5
(E,F,G), stage 12 (I–K), or stage 21 (M–O), and probed
with either digoxigenin-labeled Bmp4 (A–L) or digoxigenin-
labeled Nrp1 (M–P). Uninjected ectoderm
provides a negative control (C,G,K,O) and whole
embryos indicate the normal pattern of expression
(D,H,L,P). Arrows in D, H and L indicate the dorsal
lip of the blastopore. Image published in: Baker JC et al. (1999) Copyright © 1999. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Larger Image Printer Friendly View |