Xenbase Image ID: 135937

Fig. 8. The CASZ1 CID domain disrupts heart development. (A-D) Control embryos at early tadpole stage (stage 37) exhibit looping and formation of the cardiac chambers. v, ventricle; o, outflow tract; i, inflow tract. (E-L) CASZ1 and CASZ1 CID misexpressing embryos display incomplete convergence of the outflow and inflow tract, as seen in dorsal views (I,K) (arrowheads), and a partially closed inflow tract, as seen in posterior views (H,L) (arrowheads). n=23 for CASZ1 mis; n=29 for CASZ1 CID mis; two biological replicates. Scale bars: 100 μm. Image published in: Sojka S et al. (2014) Copyright © 2014. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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