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Figure 4. Cm-XBMP-7 induces cement glands in animal cap ectoderm. Animal cap explants from embryos injected with dominant- negative constructs. Uninjected control animal caps, at stage 35 equivalent, remain as atypical epidermis (A). Animal cap explants, at stage 35 equivalent, from Cm- XBMP-7 mRNA (0.8 ng)-injected embryos differentiate into cement glands (BJ, as revealed by pigment aggregation. (C] Histological sections of animal caps from Cm- XBMP-7 injected embryos at stage 40 equivalent. Open arrows indicate ectopic cement glands. (D) Coinjection of wild-type XBMP-7 mRNA (0.8 ng) with Cm-XBMP-7 mRNA (0.8 ng] blocks cement gland formation. (E) Ectopic expression of wild-type activin mRNA (0.5 ng) results in elongation of animal cap explants. (F) Coinjection of wildtype activin mRNA (0.5 ng] with Cm-activin mRN

Image published in: Hawley SH et al. (1995)

Copyright © 1995. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article.

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