XB-IMG-136029
Xenbase Image ID: 136029
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Figure 7. Neuralization by Cm-XBMPs is rescued by either
wild-type XBMP-7 or XBMP-4. RT-PCR analysis of N-CAM,
Xbra, and keratin markers using RNA samples isolated at stage
30 equivalent. Whole control embryos (lane I ) and uninjected
control animal caps (lane 2). Although ectopic expression of
Cm-XBMP-7 mRNA (0.8 ng) induces N-CAM and inhibits keratin
expression (lane 31, coinjection with wild-type XBMP-7
[lane 4) or XBMP-4 (lane 5) mRNA (0.8 ng) blocks neural induction
and rescues keratin expression. Ectopic expression of Cm-
XBMP-4 mRNA also induces N-CAM [lane 61, and coinjection
with wild-type XBMP-4 (lane 7) or XBMP-7 [lane 8) mRNA (0.8
ng) again represses neural induction. Image published in: Hawley SH et al. (1995) Copyright © 1995. Image reproduced on with permission of the Publisher, Cold Spring Harbor Laboratory Press. This is an Open Access article. Larger Image Printer Friendly View |