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Figure 1. Phylogenetic View of Deuterostomes and RARs(A) Current view of deuterostome phylogeny with amphioxus representing the basal chordate [5]. RARs used in the present study are indicated at their respective taxonomic positions—for mouse, Xenopus, zebrafish, lamprey, amphioxus, and tunicates. The position of the synthetic ancestral sequence is indicated by a red circle. The two proposed periods of whole genome duplications in vertebrates are indicated as Phase I and Phase II, occurring respectively before and after the divergence of lampreys.(B) Phylogenetic tree showing the placement of the RARs used in this study. Branch length is proportional to evolutionary change (bar = 0.1 substitutions per site); numbers at nodes are bootstrap support, in percent of 1,000 replicates. Branches supported by bootstrap lower than 70% have been polytomised. The tree was rooted by the amphioxus sequence, in agreement with [5]. Species abbreviations and their groups are indicated as follows. Amphioxus: Amphi, Branchiostoma floridae. Tunicates: Pm, Polyandrocarpa misakiensis; Ci, Ciona intestinalis. Lampreys: Lamp, Petromyzon marinus. Teleost fish: Takifugu, Takifugu rubripes; Tetraodon, Tetraodon nigroviridis; and Danio, Danio rerio. Amphibians: Xenopus, Xenopus laevis; Ambystoma, Ambystoma mexicanum; and Notophthalmus, Notophthalmus viridescens. Birds: Gallus, Gallus gallus; and Coturnix, Coturnix coturnix. Mammals: Homo, Homo sapiens; Mus, Mus musculus; and Rattus, Rattus norvegicus.

Image published in: Escriva H et al. (2006)

Copyright: © 2006 Escriva et al. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license

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