Xenbase Image ID: 136835

Fig. 1. High-resolution transcriptional profiling in early Xenopus tropicalis development. (A) Embryos were sampled in groups of 50 (Series 1 and 2) or ten (Series 3) at 30-min intervals between fertilisation and early gastrulation and used to generates RNA-seq libraries for Illumina sequencing. Series 3 is scaled to the development rate of Series 1 and 2 (see text). (B-D) Expression profiles constructed from time series data. Gene families (Series 1/2): (B) Wnt; (C) Foxa and Foxi. (D) Pluripotency factors (Series 3) shown to amplify MBT in zebrafish (Lee et al., 2013). (E) Gene onset detection requires a run of successive data points, each exceeding the one before by more than is likely to have occurred by chance (see Materials and methods). Stage diagrams reproduced from Nieuwkoop and Faber (Nieuwkoop and Faber, 1994) with permission of Garland Science/Taylor & Francis, LLC. Image published in: Collart C et al. (2014) © 2014. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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