XB-IMG-137010
Xenbase Image ID: 137010
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Figure 5. Action of MPC088 on retinal ganglion cellsa: Potentiation data obtained with trans- and cis-dominant MPC088; the cis-dominant preparation was obtained by pre-treating trans-dominant MPC088 with UV light for 5 min. Representative responses obtained from a single cell treated with 200 μM GABA (black), 2 μM GABA (red), 2 μM GABA co-applied with 10 μM of trans-dominant (blue) or cis-dominant (magenta) MPC088. Inset: Aggregate data (mean ± SD) for potentiation factor determined with trans- and cis-dominant MPC088 (left and right bars, respectively) (n=6, p = 0.003). b: Direct activation data obtained with trans- and cis-dominant MPC088. Representative responses obtained from a cell treated with 200 μM GABA (black), 60 μM of trans-dominant (blue) and 60 μM of cis-dominant (magenta) MPC088. Inset: Aggregate data (mean ± SD) for direct activation by MPC088. Left, middle and right bars show results obtained, respectively, with 30 μM trans-dominant (n=3), 60 μM trans-dominant (n=7), and 60 μM cis-dominant MPC088 (n=4). Image published in: Yue L et al. (2012) Image downloaded from an Open Access article in PubMed Central. Image reproduced on Xenbase with permission of the publisher and the copyright holder. Larger Image Printer Friendly View |