Xenbase Image ID: 137411

Figure 4. Dynamics of proteome and transcriptome in early Xenopus embryogenesis. (A) Schematic depiction of the workflow (upper panel) and the calculated protein content of X. leavis egg and embryo 10.5 (lower panel). (B) Unsupervised correlation-based clustering of egg and embryo 10.5 proteomes clearly separates egg and embryo 10.5 proteomes. (C) Heatmap of significant regulated proteins between egg and embryo 10.5, identified by an adapted t-test (FDR = 0.005 and s0 = 1). (D) Enriched GO terms for both egg and embryo 10.5 enriched proteins, as identified in C. Y-axis represents the –log FDR. (E) Protein and mRNA ratios (egg/embryo 10.5) for both egg (left panel) and embryo 10.5 (right panel) enriched proteins reveal lack of correlation between protein and mRNA dynamics. See also Supplementary Table S4. Image published in: Smits AH et al. (2014) © The Author(s) 2014. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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