Xenbase Image ID: 137788

Figure 1. Intracellular ATP does not inhibit ISlo2.1 recorded from inside‐out macropatches of Xenopus oocyte membranes. (A) Representative current traces recorded from excised inside‐out macropatches of oocyte membrane during voltage ramps (upper inset) from +80 to −120 mV. Currents were recorded in the absence (Control, black trace), 5 min after addition of 5 mmol/L K2ATP (red trace), and after addition of 100 μM D890 in the continued presence of K2ATP. Arrow indicates 0 current level. (B) Mean currents from 30 to 35 consecutive sweeps under each condition as indicated. (C) Bar graph comparing normalized peak ISlo2.1 in the absence and presence of 5 mmol/L K2ATP. No statistical difference was observed between the two groups (paired Student's t test; P = 0.13, n = 4). Image published in: Garg P and Sanguinetti MC (2014) © 2014 The Authors. This image is reproduced with permission of the journal and the copyright holder. This is an open-access article distributed under the terms of the Creative Commons Attribution license Larger Image Printer Friendly View

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