XB-IMG-137993
Xenbase Image ID: 137993
FIG. 3. Mapping of the Smad-binding
domain in SIP1. Schematic representation
of deletion constructs to map
the segment required for interaction of
SIP1 with the XSmad1 MH2 domain. The
original Smad-binding domain (spanning
amino acids 315–507; shown in brown)
was used as a starting point for the detailed
mapping. The right column summarizes
interaction data obtained in
yeast, as assayed by ability to grow on
plates lacking histidine and in the presence
of 5 mM 3-amino-triazole and by
staining of b-galactosidase. The Smadbinding
domain (SBD, shown in green) is
a 51-amino acids-long peptide defined as
essential for the interaction; its amino
acid sequence (aa seq) is shown in the
lower part of the figure. Image published in: Verschueren K et al. (1999) Copyright © 1999. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View |